Rosie O’Donnell and Celebrities Praise Mounjaro for Weight Loss
In a surprising update, Rosie O’Donnell announced her significant weight loss journey in May 2025, attributing her success to Mounjaro (tirzepatide), a medication originally designed for diabetes treatment but increasingly recognized for its weight loss benefits. O’Donnell opened up on Instagram, stating, “I can’t believe this is me now,” showcasing her transformation since moving to Ireland.
The former talk show host began using Mounjaro for her diabetes, but the added bonus of weight loss made a remarkable difference. Other public figures have also embraced Mounjaro, including Whoopi Goldberg, who shared her journey on The Kelly Clarkson Show, revealing that she lost the weight equivalent to "almost two people." Comedian Amy Schumer also praised the drug, noting that it worked better for her than previous medications, adding that hormonal treatments tailored to her perimenopausal stage complemented her efforts.
The conversation around Mounjaro isn’t isolated to O’Donnell and Goldberg. Other celebrities, like Meghan Trainor and Daryl Sabara, have also reported positive experiences with the drug while emphasizing mindful eating and portion control in their lifestyle changes. Scott Disick confidently acknowledged his use of Mounjaro on The Kardashians, dismissing any stigma attached to weight loss medications.
As various stars embrace the medication, discussions about its potential side effects, such as nausea and diarrhea, continue. However, the overwhelming message from these celebrities is one of empowerment, encouraging others on their weight loss journeys. Ex-reality star Renee Graziano highlighted that overcoming her insecurities and sharing her transformation is what motivates her to inspire others.
As more public figures advocate for Mounjaro, it appears to be making significant waves in the ever-evolving landscape of weight management and health.
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